BONE DISEASE IN PRIMARY HYPERCALCIURIA
نویسندگان
چکیده
منابع مشابه
Bone metabolism in primary hypercalciuria
Primary Hypercalciuria (PH) is very frequently accompanied by some degrees of bone demineralization. The most frequent clinical condition in which this association has been studied is calcium nephrolithiasis. In these patients bone density has been reported to be very frequently low and increased susceptibility to fragility fractures has been described. One of the most important aspects is the ...
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Observational and epidemiologic studies alike have shown that idiopathic hypercalciuric (IH) stone-forming patients typically show bone mineral density scores that are significantly lower than those observed for age- and sex-matched normal subjects or those for nonhypercalciuric stone-forming patients. Most of these studies have relied on changes in bone mineral density and have not explored th...
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Key words: bone mineral density; hypercalciuria; panied by decreased osteoblastic surfaces, while others, have reported reduced bone formation, increased bone osteoporosis; renal stone disease; urolithiasis resorption and a severe mineralization defect [4]. In a recent retrospective analysis of bone mineral density by dual X-ray absorptiometry, we compared a
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Hypercalciuria may be classified into absorptive, renal and resorptive forms, depending on whether the primary defect is intestinal hyperabsorption of calcium, renal leak of calcium, or excessive bone resorption. In absorptive hypercalciuria, the pathogenetic role of vitamin D is uncertain, and mutations in the chloride channel may occur mainly in association with Dent’s disease. Early studies ...
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Prevalence of hypercalciuria is markedly increased in patients with calcium kidney stones, and recently it has been demonstrated that the risk to produce stones is positively related with the levels of calcium excretion in general population. The stonepromoting effect of hypercalciuria depends on the unusually high calcium concentrations in urine and tubular fluid, which favor calcium salt prec...
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ژورنال
عنوان ژورنال: Critical Reviews in Clinical Laboratory Sciences
سال: 2005
ISSN: 1040-8363,1549-781X
DOI: 10.1080/10408360590913533